Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Tumor 246 articles

Articles

Is It Possible and Safe to Perform Acetabular-preserving Resections for Malignant Neoplasms of the Periacetabular Region?

Ying-lee Lam FHKAM, Raymond Yau FHKAM, Kenneth W. Y. Ho FHKAM, Ka-lok Mak FHKAM, Sin-tak Fong FHKAM, Timothy Y. C. So FHKAM

Primary malignant tumors located near the acetabulum are usually managed by resection of the tumor with wide margins that include the acetabulum. These resections are deemed P2 resections by the Enneking and Dunham classification. There are various methods to perform the subsequent hip reconstruction. Unfortunately, there is no consensus as to the best management. In general, patients undergoing resection at this level will have substantial levels of pain and disability as measured by the Musculoskeletal Tumor Society (MSTS) scoring system. We believe there is a subset of patients whose tumors in this location can be resected while preserving all or most of the weightbearing acetabulum using navigation and careful surgical planning.

What Sport Activity Levels Are Achieved in Patients After Resection and Endoprosthetic Reconstruction for a Proximal Femur Bone Sarcoma?

Gerhard M. Hobusch MD, Jakob Bollmann CM, Stephan E. Puchner MD, Nikolaus W. Lang MD, Jochen G. Hofstaetter MD, Philipp T. Funovics MD, MSc, Reinhard Windhager MD

Limited information is available about sports activities of survivors after resection and reconstruction of primary malignant bone tumors with megaprostheses. Because patients often ask what activities are possible after treatment, objective knowledge about sports activities is needed to help assess the risks of sports participation and to help guide patients’ expectations.

Survival in Mesenchymal Chondrosarcoma Varies Based on Age and Tumor Location: A Survival Analysis of the SEER Database

Brian A. Schneiderman MD, Stephanie A. Kliethermes PhD, Lukas M. Nystrom MD

Studies suggest that mesenchymal chondrosarcoma is associated with a poorer prognosis and a higher proportion of extraskeletal tumors than conventional chondrosarcoma. However, these investigations have been small heterogeneous cohorts, limiting analysis of prognostic factors.

What Are the Conditional Survival and Functional Outcomes After Surgical Treatment of 115 Patients With Sacral Chordoma?

Tao Ji MD, Wei Guo MD, PhD, Rongli Yang MD, Xiaodong Tang MD, Yifei Wang MD, Lin Huang MD

Conditional survival is a measure of prognosis for patients who have already survived for a specific period of time; however, data on conditional survival after sacrectomy in patients with sacral chordoma are lacking. In addition, because sacral tumors are rare and heterogeneous, classifying them in a way that allows physicians to predict functional outcomes after sacrectomy remains a challenge.

What Factors Are Associated With Failure of Compressive Osseointegration Fixation?

Ryland Kagan MD, Jacob Adams MD, Caroline Schulman BE, Rachel Laursen BS, Karina Espana BS, Jung Yoo MD, Yee-Cheen Doung MD, James Hayden MD, PhD

Compressive osseointegration is as an alternative to traditional intramedullary fixation. Two- to 10-year survivorship and modes of failure have been reported; however, as a result of relatively small numbers, these studies are limited in their ability to identify risk factors for failure.

Has the Level of Evidence of Podium Presentations at the Musculoskeletal Tumor Society Annual Meeting Changed Over Time?

Daniel M. Lerman MD, Matthew G. Cable MD, Patrick Thornley BHSc, Nathan Evaniew MD, Gerard P. Slobogean MD, Mohit Bhandari MD, MSc, PhD, John H. Healey MD, R. Lor Randall MD, Michelle Ghert MD

Level of evidence (LOE) framework is a tool with which to categorize clinical studies based on their likelihood to be influenced by bias. Improvements in LOE have been demonstrated throughout orthopaedics, prompting our evaluation of orthopaedic oncology research LOE to determine if it has changed in kind.

What Is the Expected Learning Curve in Computer-assisted Navigation for Bone Tumor Resection?

Germán L. Farfalli MD, José I. Albergo MD, Lucas E. Ritacco MD, Miguel A. Ayerza MD, Federico E. Milano MSC, Luis A. Aponte-Tinao MD

Computer navigation during surgery can help oncologic surgeons perform more accurate resections. However, some navigation studies suggest that this tool may result in unique intraoperative problems and increased surgical time. The degree to which these problems might diminish with experience–the learning curve–has not, to our knowledge, been evaluated for navigation-assisted tumor resections.

Supplemental Bone Grafting in Giant Cell Tumor of the Extremity Reduces Nononcologic Complications

Joseph Benevenia MD, Steven M. Rivero MD, Jeffrey Moore MD, Joseph A. Ippolito BA, Daniel A. Siegerman MD, Kathleen S. Beebe MD, Francis R. Patterson MD

Giant cell tumors (GCTs) are treated with resection curettage and adjuvants followed by stabilization. Complications include recurrence, fracture, and joint degeneration. Studies have shown treatment with polymethylmethacrylate (PMMA) may increase the risk of joint degeneration and fracture. Other studies have suggested that subchondral bone grafting may reduce these risks.

Reconstruction After Hemipelvectomy With the Ice-Cream Cone Prosthesis: What Are the Short-term Clinical Results?

Irene Barrientos-Ruiz MD, Eduardo José Ortiz-Cruz MD, Manuel Peleteiro-Pensado MD

Reconstruction after internal hemipelvectomy resection likely provides better function than hindquarter amputation. However, many reconstruction methods have been used, complications with these approaches are common, and function often is poor; because of these issues, it seems important to investigate alternative implants and surgical techniques.

Do Patients After Chondrosarcoma Treatment Have Age-appropriate Bone Mineral Density in the Long Term?

Gerhard M. Hobusch MD, Thomas M. Tiefenboeck MD, Janina Patsch MD, Christoph Krall MD, Gerold Holzer MD

In long-term survivors of osteosarcoma and Ewing sarcoma treated with the addition of radio- and chemotherapy, low bone mineral density (BMD) and fractures have been observed, presumably resulting from these adjuvants. Because patients with chondrosarcoma usually are not treated with conventional adjuvant treatment, observation of low BMD in patients with chondrosarcoma presumably would be the result of other mechanisms. However, BMD in patients with a history of chondrosarcoma has not been well characterized.