Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Tumor 242 articles


Does Combined Open and Arthroscopic Synovectomy for Diffuse PVNS of the Knee Improve Recurrence Rates?

Matthew W. Colman MD, Jason Ye MD, Kurt R. Weiss, Mark A. Goodman MD, Richard L. McGough MD

Diffuse-type pigmented villonodular synovitis (PVNS) has a high local recurrence rate and as such can lead to erosive destruction of the involved joint. Multiple surgical modalities exist, but it is unknown which technique best minimizes local recurrence and surgical morbidity.

Orthopaedic Case of the Month: Painless Right Knee Mass in 32-year-old Man

Michael K. Merz MD, Mansooreh Eghtesadghalati MD, Michael E. Bresler MD, Yasser R. Farid MD, PhD

Treating Metastatic Disease: Which Survival Model Is Best Suited for the Clinic?

Jonathan Agner Forsberg MD, Daniel Sjoberg MA, Qing-Rong Chen PhD, Andrew Vickers PhD, John H. Healey MD

To avoid complications associated with under- or overtreatment of patients with skeletal metastases, doctors need accurate survival estimates. Unfortunately, prognostic models for patients with skeletal metastases of the extremities are lacking, and physician-based estimates are generally inaccurate.

Making a Case for the Socioeconomic Determinacy of Survival in Osteosarcoma

Saminathan S. Nathan FRCS, John H. Healey FACS

The literature on osteosarcoma survival generally focuses on tumor and treatment variables, although it is unclear whether and how ethnic and socioeconomic factors might influence survival.

Primary Osseous Tumors of the Hindfoot: Why the Delay in Diagnosis and Should We Be Concerned?

Peter S. Young MRCS, Stuart W. Bell MRCS, MRCP, Elaine M. MacDuff BSc, MBChB, FRCPath, Ashish Mahendra FRCS Tr & Orth

Bony tumors of the foot account for approximately 3% of all osseous tumors. Diagnosis is frequently delayed as a result of lack of clinician familiarity and as a result of their rarity. The reasons for the delays, however, are unclear.

Adult Soft Tissue Sarcoma Local Recurrence After Adjuvant Treatment Without Resection of Core Needle Biopsy Tract

Odion Binitie MD, Shawn Tejiram MD, Sheila Conway MD, David Cheong MD, H. Thomas Temple MD, G. Douglas Letson MD

Core needle biopsies of sarcomas allow a diagnosis in a high percentage of patients with few complications. However, it is unclear whether the tract needs to be excised to prevent recurrences.

Lymphadenectomy and Histologic Subtype Affect Overall Survival of Soft Tissue Sarcoma Patients With Nodal Metastases

Chigusa Sawamura MD, MPH, Seiichi Matsumoto MD, PhD, Takashi Shimoji MD, PhD, Keisuke Ae MD, PhD, Atsushi Okawa MD, PhD

Lymph node metastases in patients with soft tissue sarcomas are rare and these metastases are frequently associated with certain histologic subtypes. The survival is believed to be poor if lymph node metastases occur and the potential benefit of lymphadenectomy is unclear.

A Novel Imaging System Permits Real-time in Vivo Tumor Bed Assessment After Resection of Naturally Occurring Sarcomas in Dogs

William C. Eward DVM, MD, Jeffrey K. Mito MD, PhD, Cindy A. Eward DVM, Jessica E. Carter, Jorge M. Ferrer PhD, David G. Kirsch MD, PhD, Brian E. Brigman MD, PhD

Treatment of soft tissue sarcoma (STS) includes complete tumor excision. However, in some patients, residual sarcoma cells remain in the tumor bed. We previously described a novel hand-held imaging device prototype that uses molecular imaging to detect microscopic residual cancer in mice during surgery.

Which Implant Is Best After Failed Treatment for Pathologic Femur Fractures?

Jonathan Agner Forsberg MD, Rikard Wedin MD, PhD, Henrik Bauer MD, PhD

Successful treatment of pathologic femur fractures can preserve a patient’s independence and quality of life. The choice of implant depends on several disease- and patient-specific variables; however, its durability must generally match the patient’s estimated life expectancy. Failures do occur, however, it is unclear which implants are associated with greater risk of failure.