Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Tumor 245 articles

Articles

Paley’s Multiplier Method Does Not Accurately Predict Adult Height in Children with Bone Sarcoma

Magdalena Maria Gilg MD, Christine Wibmer MD, Dimosthenis Andreou MD, Alexander Avian PhD, Petra Sovinz MD, Werner Maurer-Ertl MD, Per-Ulf Tunn MD, Andreas Leithner MD

The majority of patients with osteosarcoma and Ewing’s sarcoma are diagnosed before skeletal maturity. Paley’s multiplier is used for height prediction in healthy children, and has been suggested as a method to make growth predictions for children with osteosarcoma and Ewing’s sarcoma when considering limb salvage options. To our knowledge, no evaluation of this method in this particular patient group has been performed, but a temporary growth deficit has been observed in children undergoing chemotherapy.

Does Total Humeral Endoprosthetic Replacement Provide Reliable Reconstruction With Preservation of a Useful Extremity?

Hazem Wafa FRCSEd(Tr & Orth), Krishna Reddy FRCSEd(Tr & Orth), Robert Grimer DSc, Adesegun Abudu FRCS(Tr & Orth), Lee Jeys FRCS(Tr & Orth), Simon Carter FRCS, Roger Tillman FRCS(Tr & Orth)

Controversy exists regarding the ideal method of reconstruction after proximal humeral resection and several reconstructive techniques have been reported. The reconstructive options are very limited when resection of the entire humerus is required. One option is endoprosthetic reconstruction, but there have been few published studies on the outcome of total humeral endoprosthetic reconstruction.

Do Patients With Ewing’s Sarcoma Continue With Sports Activities After Limb Salvage Surgery of the Lower Extremity?

Gerhard Martin Hobusch MD, Nikolaus Lang MD, Reinhard Schuh MD, Reinhard Windhager MD, Jochen Gerhard Hofstaetter MD

Limb salvage surgery has evolved to become the standard method of treating sarcomas of the extremities with acceptable oncologic results. However, little information exists relative to the activity level or ability to participate in sports after tumor reconstructions.

Does Intraoperative Navigation Assistance Improve Bone Tumor Resection and Allograft Reconstruction Results?

Luis Aponte-Tinao MD, Lucas E. Ritacco MD, Miguel A. Ayerza MD, D. Luis Muscolo MD, Jose I. Albergo MD, Germán L. Farfall MD

Bone tumor resections for limb salvage have become standard treatment. Recently, computer-assisted navigation has been introduced to improve the accuracy of joint arthroplasty and possible tumor resection surgery; however, like with any new technology, its benefits and limitations need to be characterized for surgeons to make informed decisions about whether to use it.

Estimated Cause-specific Survival Continues to Improve Over Time in Patients With Chondrosarcoma

Kyle R. Duchman MD, Charles F. Lynch MD, MS, PhD, Joseph A. Buckwalter MD, MS, Benjamin J. Miller MD, MS

Conditional survival measures change in the risk of mortality given that a patient has survived a defined period of time. This has yet to be reported for chondrosarcoma of bone. This information should be of interest to the clinician and helpful in counseling patients with chondrosarcoma.

Multilevel En Bloc Spondylectomy for Tumors of the Thoracic and Lumbar Spine Is Challenging But Rewarding

Alessandro Davide Luzzati MD, Sambhav Shah MS, Fabio Gagliano MD, Giuseppe Perrucchini MD, Gennaro Scotto MD, Marco Alloisio MD

Over the years, en bloc spondylectomy has proven its efficacy in controlling spinal tumors and improving survival rates. However, there are few reports of large series that critically evaluate the results of multilevel en bloc spondylectomies for spinal neoplasms.

Frequent Complications and Severe Bone Loss Associated With the Repiphysis Expandable Distal Femoral Prosthesis

Cara A. Cipriano MD, Irina S. Gruzinova BS, Rachel M. Frank MD, Steven Gitelis MD, Walter W. Virkus MD

The treatment of choice for distal femur malignancies in skeletally immature patients remains controversial. An expandable endoprosthesis device (Repiphysis Limb Salvage System; Wright Medical Technology, Arlington, TN, USA) allows for limb preservation and noninvasive lengthening but has been associated with significant complications; however, the extent and implications of bone loss associated with this implant have not been reported.

Is Surgery for Brachial Plexus Schwannomas Safe and Effective?

Hyuk Jin Lee MD, Jeong Hwan Kim MD, Seung Hwan Rhee MD, Hyun Sik Gong MD, Goo Hyun Baek MD, PhD

Schwannomas rarely are found in the brachial plexus, and although they are benign, they present significant challenges to surgical treatment. To our knowledge, there are few studies investigating the surgical outcomes of patients with brachial plexus tumors.

Proximal Tumor Location and Fluid-fluid Levels on MRI Predict Resistance to Chemotherapy in Stage IIB Osteosarcoma

Dae-Geun Jeon MD, Won Seok Song MD, Wan Hyeong Cho MD, Chang-Bae Kong MD, Sang Hyun Cho MD

Primary tumor growth during neoadjuvant chemotherapy is believed to be a sign of resistance to chemotherapy (chemoresistance), and often is associated with poor histologic response, local recurrence, and poorer survival. Currently there are no proven indicators to predict poor response to chemotherapy at the time of diagnosis.

Aneurysmal Bone Cysts: Do Simple Treatments Work?

Krishna I. A. Reddy MCh (Orth), FRCSEd (Orth), F. Sinnaeve MD, Czar Louie Gaston MD, Robert J. Grimer FRCS, Simon R. Carter FRCS

Primary aneurysmal bone cysts (ABCs) are benign, expansile bone lesions commonly treated with aggressive curettage with or without adjuvants such as cryotherapy, methacrylate cement, or phenol. It has been reported that occasionally these lesions heal spontaneously or after a pathologic fracture, and we observed that some ABCs treated at our center healed after biopsy alone. Because of this, we introduced a novel biopsy technique we call “curopsy,” which is a percutaneous limited curettage at the time of biopsy, obtaining the lining membrane from various quadrants of the cyst leading to consolidation (curopsy = biopsy with intention to cure).