Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Knee 443 articles


Can Arthroscopically Assisted Treatment of Chronic Patellar Tendinopathy Reduce Pain and Restore Function?

Jorge Santander MD, Eduardo Zarba MD, Horacio Iraporda MD, Sebastián Puleo MD

Patellar tendinopathy is a common source of pain in athletes, especially those involved in sports with a high incidence of jumping and cutting. Changes in training programs and exercises based on eccentric quadriceps contractions often relieve patients’ symptoms. For athletes unresponsive to this treatment, some authors suggest open and arthroscopic procedures débriding either the tendon alone, or the tendon and bone.

Patient Gender Affects the Referral and Recommendation for Total Joint Arthroplasty

Cornelia M. Borkhoff PhD, Gillian A. Hawker MD, MSc, FRCPC, James G. Wright MD, MPH, FRCSC

Rates of use of total joint arthroplasty among appropriate and willing candidates are lower in women than in men. A number of factors may explain this gender disparity, including patients’ preferences for surgery, gender bias influencing physicians’ clinical decision-making, and the patient-physician interaction.

Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA: A Prospective Randomized Controlled Trial

Keerati Charoencholvanich MD, Pichet Siriwattanasakul MD

TKA may be associated with considerable blood loss, and transfusion carries substantial risk of immunologic reaction and disease transmission. Blood transfusion also involves additional cost, therefore a reduction in its use is important. Several methods reportedly reduce postoperative blood loss and avoid homologous blood transfusion with traditional TKA approaches, but it is unclear these reductions apply to a minimally invasive technique.

Cartilage Matrix Formation by Bovine Mesenchymal Stem Cells in Three-dimensional Culture Is Age-dependent

Isaac E. Erickson BS, Steven C. Veen, Swarnali Sengupta, Sydney R. Kestle, Robert L. Mauck PhD

Cartilage degeneration is common in the aged, and aged chondrocytes are inferior to juvenile chondrocytes in producing cartilage-specific extracellular matrix. Mesenchymal stem cells (MSCs) are an alternative cell type that can differentiate toward the chondrocyte phenotype. Aging may influence MSC chondrogenesis but remains less well studied, particularly in the bovine system.

Can Wedge Osteotomy Correct Depression of the Lateral Tibial Plateau Mimicking Posterolateral Rotatory Knee Instability?

Miguel A. Ayerza MD, Federico Suarez MD, Matias Costa-Paz MD, D. Luis Muscolo MD

The literature suggests rotatory knee instability (pseudolaxity) can be associated with depressions of the lateral tibial plateau in patients despite an intact arcuate ligament complex. Correcting this bone deformity by an open-wedge osteotomy of the lateral tibia plateau, elevating the depressed bone may restore knee stability.

Degradation Improves Tissue Formation in (Un)Loaded Chondrocyte-laden Hydrogels

Justine J. Roberts BS, Garret D. Nicodemus PhD, Eric C. Greenwald MS, Stephanie J. Bryant PhD

Photopolymerizable poly(ethylene glycol) (PEG) hydrogels offer a platform to deliver cells in vivo and support three-dimensional cell culture but should be designed to degrade in sync with neotissue development and endure the physiologic environment.

Does High Tibial Osteotomy Affect the Success or Survival of a Total Knee Replacement?

John B. Meding MD, Jennifer T. Wing, Merrill A. Ritter MD

Whether a previous high tibial osteotomy (HTO) influences the long-term function or survival of a total knee arthroplasty (TKA) is controversial.

2010 Mid-America Orthopaedic Association Physician in Training Award: Predictors of Early Adverse Outcomes after Knee and Hip Arthroplasty in Geriatric Patients

Carlos A. Higuera MD, Karim Elsharkawy MD, MRCS, Alison K. Klika MS, Matthew Brocone BS, Wael K. Barsoum MD

Geriatric patients experience more adverse events owing to early complications after TKA or THA related to preexisting comorbidities. However, associations between patient and surgery variables, including age, BMI, and comorbidities with complications are unclear. Knowing these relationships is necessary for developing risk stratification, defining contraindications, and predicting complications and adverse outcomes.

Is Noncontact ACL Injury Associated with the Posterior Tibial and Meniscal Slope?

R. Hudek MD, B. Fuchs MD, PhD, F. Regenfelder MD, P. P. Koch MD

The risk of noncontact ACL injury reportedly is increased in patients with a greater posterior tibial slope (PTS), but clinical data are inconsistent. It is unclear whether the medial and lateral PTSs have a different impact on this connection. It also is unknown whether the meniscal slope (MS) is associated with ACL injury.

Does Tranexamic Acid Save Blood in Minimally Invasive Total Knee Arthroplasty?

Po-Chun Lin MD, Chi-Hsiang Hsu MD, Wun-Schen Chen MD, Jun-Wen Wang MD

Tranexamic acid (TEA) reportedly reduces perioperative blood loss in TKA. However, whether it does so in minimally invasive TKA is not clear.