Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Knee 450 articles


Platelet-rich Plasma in Meniscal Repair: Does Augmentation Improve Surgical Outcomes?

Justin W. Griffin MD, Michael M. Hadeed MD, Brian C. Werner MD, David R. Diduch MD, Eric W. Carson MD, Mark D. Miller MD

Increased contact stresses after meniscectomy have led to an increased focus on meniscal preservation strategies to prevent articular cartilage degeneration. Platelet-rich plasma (PRP) has received attention as a promising strategy to help induce healing and has been shown to do so both in vitro and in vivo. Although PRP has been used in clinical practice for some time, to date, few clinical studies support its use in meniscal repair.

Is There an Advantage to Knotless Barbed Suture in TKA Wound Closure? A Randomized Trial in Simultaneous Bilateral TKAs

Alexander P. Sah MD

Effective wound closure is critical to minimizing wound complications and withstanding the forces associated with early knee motion after TKA. Barbed sutures allow for knotless fixation, have been used successfully in other specialties, and may provide for more even distribution of tension along the length of the incision; however, data regarding unidirectional barbed sutures from randomized trials have raised important concerns about their use. Bidirectional barbed sutures offer a potential alternative, but have not been studied extensively in orthopaedic surgery.

What Is the Effect of Matrices on Cartilage Repair? A Systematic Review

James D. Wylie MD, Melissa K. Hartley BA, Ashley L. Kapron PhD, Stephen K. Aoki MD, Travis G. Maak MD

Articular cartilage has minimal endogenous ability to undergo repair. Multiple chondral restoration strategies have been attempted with varied results.

Lateral Opening-wedge Distal Femoral Osteotomy: Pain Relief, Functional Improvement, and Survivorship at 5 Years

James I. Cameron MD, Julie C. McCauley MPHc, Arash Y. Kermanshahi MD, William D. Bugbee MD

Distal femoral varus osteotomy may be used to treat valgus knee malalignment or to protect a knee compartment in which cartilage restoration surgery (such as osteochondral or meniscus allografting) has been performed. Medial closing-wedge osteotomy has demonstrated good success in treatment of osteoarthritis in published series, but few studies have evaluated distal femoral lateral opening-wedge osteotomy in terms of correction of deformity, pain and function, and survivorship.

No Sex Differences Exist in Posterior Condylar Offsets of the Knee

Pramod B. Voleti MD, Jason W. Stephenson MD, Paul A. Lotke MD, Gwo-Chin Lee MD

Restoration of posterior condylar offset during TKA is believed to be important to improving knee kinematics, maximizing ROM, and minimizing flexion instability. However, controversy exists regarding whether there are important anatomic differences between sexes and whether a unisex knee prosthesis can restore the anatomy of knees in males and females.

Do Glycemic Markers Predict Occurrence of Complications After Total Knee Arthroplasty in Patients With Diabetes?

Ji Sup Hwang BE, Seok Jin Kim MD, Ankur B. Bamne MS (Orth), Young Gon Na MD, Tae Kyun Kim MD, PhD

Patients with diabetes have increased risk of infections and wound complications after total knee arthroplasty (TKA). Glycemic markers identifying patients at risk for complications after TKA have not yet been elucidated.

Is There a Difference in Total Knee Arthroplasty Risk of Revision in Highly Crosslinked versus Conventional Polyethylene?

Elizabeth W. Paxton MA, Maria C. S. Inacio PhD, Steven Kurtz PhD, Rebecca Love MPH, RN, Guy Cafri PhD, Robert S. Namba MD

Highly crosslinked polyethylene (HXLPE) was introduced to reduce wear and associated osteolysis in total knee arthroplasty (TKA). However, there is limited clinical evidence that HXLPE is more effective than conventional polyethylene (CPE) in TKA.

Injury Risk to Extraosseous Knee Vasculature During Osteotomies: A Cadaveric Study With CT and Dissection Analysis

Salvatore Bisicchia MD, Federica Rosso MD, Marc A. Pizzimenti PhD, Chamnanni Rungprai MD, Jessica E. Goetz PhD, Annunziato Amendola MD

Realignment osteotomies about the knee may be performed as distal femoral or proximal tibial osteotomies; both may be performed either on the medial or lateral sides of the knee, in closing- or opening-wedge fashion. Although rare, injury to neurovascular structures may occur, and the proximity of the vascular structures to the osteotomy saw cuts has been incompletely characterized.

Abnormal Quantitative Sensory Testing is Associated With Persistent Pain One Year After TKA

Anthony Wright PhD, Penny Moss PhD, Karen Sloan MSc, Richard J. Beaver FRACS, Jarle B. Pedersen MClinPhysio, Gerard Vehof MClinPhysio, Henrik Borge MClinPhysio, Luca Maestroni MClinPhysio, Philip Cheong MManipTher

Up to 15% of patients report at least moderate persistent pain after TKA. Such pain may be associated with the presence of widespread hyperalgesia and neuropathic-type pain.

Validation of Porcine Knee as a Sex-specific Model to Study Human Anterior Cruciate Ligament Disorders

Ata M. Kiapour PhD, Matthew R. Shalvoy BS, Martha M. Murray MD, Braden C. Fleming PhD

Animal models have long been considered an important modality for studying ACL injuries. However, to our knowledge, the value of these preclinical models to study sex-related phenomena associated with ACL injury and recovery has not been evaluated.