Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Hip 725 articles


How Have New Bearing Surfaces Altered the Local Biological Reactions to Byproducts of Wear and Modularity?

Thomas W. Bauer MD, PhD, Patricia A. Campbell PhD, Gretchen Hallerberg MS, MSLS, AHIP

The biologic reactions to byproducts of wear or corrosion can involve innate and adaptive processes and are dependent on many factors, including the composition, size, surface properties, shape, and concentration of debris.

How Have Alternative Bearings and Modularity Affected Revision Rates in Total Hip Arthroplasty?

William M. Mihalko MD, PhD, Markus A. Wimmer PhD, Carol A. Pacione BS, Michel P. Laurent PhD, Robert F. Murphy MD, Carson Rider BS

Total hip arthroplasty (THA) continues to be one of the most successful surgical procedures in the medical field. However, over the last two decades, the use of modularity and alternative bearings in THA has become routine. Given the known problems associated with hard-on-hard bearing couples, including taper failures with more modular stem designs, local and systemic effects from metal-on-metal bearings, and fractures with ceramic-on-ceramic bearings, it is not known whether in aggregate the survivorship of these implants is better or worse than the metal-on-polyethylene bearings that they sought to replace.

Modular Tapered Implants for Severe Femoral Bone Loss in THA: Reliable Osseointegration but Frequent Complications

Nicholas M. Brown MD, Matthew Tetreault MD, Cara A. Cipriano MD, Craig J. Della Valle MD, Wayne Paprosky MD, Scott Sporer MD

Modular tapered stems have been suggested as the optimal implants for patients with severe femoral bone loss (Paprosky Type IIIB and IV) undergoing revision total hip arthroplasty (THA); however, there are few data describing survivorship and hip scores associated with this treatment.

Patient-Specific Anatomical and Functional Parameters Provide New Insights into the Pathomechanism of Cam FAI

K. C. Geoffrey Ng MASc, Mario Lamontagne PhD, Andrew P. Adamczyk MSc, Kawan S. Rahkra MD, Paul E. Beaulé MD

Femoroacetabular impingement (FAI) represents a constellation of anatomical and clinical features, but definitive diagnosis is often difficult. The high prevalence of cam deformity of the femoral head in the asymptomatic population as well as clinical factors leading to the onset of symptoms raises questions as to what other factors increase the risk of cartilage damage and hip pain.

Revisions of Monoblock Metal-on-metal THAs Have High Early Complication Rates

Louis S. Stryker MD, Susan M. Odum PhD, Thomas K. Fehring MD, Bryan D. Springer MD

A relatively high percentage of monoblock metal-on-metal total hip arthroplasties (THAs) undergo early revision. Revision of these THAs poses challenges unique to this implant type. The early complications after these revisions remain unreported as do the clinical and demographic factors associated with these complications.

Benefit of Cup Medialization in Total Hip Arthroplasty is Associated With Femoral Anatomy

Alexandre Terrier PhD, Francesc Levrero Florencio MSc, Hannes A. Rüdiger MD

Medialization of the cup with a respective increase in femoral offset has been proposed in THA to increase abductor moment arms. Insofar as there are potential disadvantages to cup medialization, it is important to ascertain whether the purported biomechanical benefits of cup medialization are large enough to warrant the downsides; to date, studies regarding this question have disagreed.

The Otto Aufranc Award: Modifiable versus Nonmodifiable Risk Factors for Infection After Hip Arthroplasty

Guy Maoz MD, Michael Phillips MD, Joseph Bosco MD, James Slover MD, MS, Anna Stachel MPH, Ifeoma Inneh MPH, Richard Iorio MD

Periprosthetic joint infections (PJIs) are associated with increased morbidity and cost. It would be important to identify any modifiable patient- and surgical-related factors that could be modified before surgery to decrease the risk of PJI.

Are Biologic Treatments a Potential Approach to Wear- and Corrosion-related Problems?

R. Lane Smith PhD, Edward M. Schwarz PhD

Biological treatments, defined as any nonsurgical intervention whose primary mechanism of action is reducing the host response to wear and/or corrosion products, have long been postulated as solutions for osteolysis and aseptic loosening of total joint arthroplasties. Despite extensive research on drugs that target the inflammatory, osteoclastic, and osteogenic responses to wear debris, no biological treatment has emerged as an approved therapy. We review the extensive preclinical research and modest clinical research to date, which has led to the central conclusion that the osteoclast is the primary target. We also allude to the significant changes in health care, unabated safety concerns about chronic immunosuppressive/antiinflammatory therapies, industry’s complete lack of interest in developing an intervention for this condition, and the practical issues that have narrowly focused the possibilities for a biologic treatment for wear debris-induced osteolysis.

Twenty-year Followup of an Uncemented Stem in Primary THA

John B. Meding MD, Merrill A. Ritter MD, E. Michael Keating MD, Michael E. Berend MD

Uncemented stems have been used in THA for well over two decades, but there are relatively few studies reporting on the results after 20 years.

Femoroacetabular Impingement Negates the Acetabular Labral Seal During Pivoting Maneuvers but Not Gait

Maureen K. Dwyer PhD, ATC, Hugh L. Jones BS, Richard E. Field PhD, FRCS (Orth), FRCS, Joseph C. McCarthy MD, Philip C. Noble PhD

Experimental disruption of the labrum has been shown to compromise its sealing function and alter cartilage lubrication. However, it is not known whether pathological changes to the labrum secondary to femoroacetabular impingement (FAI) have a similar impact on labral function.