Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Online First™

Articles

What is the Ideal Route of Administration of Tranexamic Acid in TKA? A Randomized Controlled Trial

Sung Yup Lee MD, Suri Chong MD, Dhanasekaraprabu Balasubramanian MS (Orth), Young Gon Na MD, Tae Kyun Kim MD, PhD
10th March 2017, Clinical Research

TKA commonly involves substantial blood loss and tranexamic acid has been used to reduce blood loss after TKA. Numerous clinical trials have documented the efficacy and safety of intravenous (IV) or intraarticular (IA) use of tranexamic acid. Combined administration of tranexamic acid also has been suggested; however, there is no consensus regarding the ideal route of tranexamic acid administration.

Débridement and Reconstruction Improve Postoperative Sagittal Alignment in Kyphotic Cervical Spinal Tuberculosis

Zhimin Pan MD, Jiaquan Luo MD, PhD, Limin Yu MD, PhD, Yiwei Chen MD, Junlong Zhong MD, Zhiyun Li MD, PhD, Zhaoxun Zeng MD, Pingguo Duan MD, PhD, Yoon Ha MD, PhD, Kai Cao MD, PhD
6th March 2017, Clinical Research

Cervical spinal tuberculosis is relatively common in some developing countries. It erodes vertebrae and discs, which sometimes results in cervical kyphosis and myelopathy. However, to our knowledge, no studies have evaluated improvements to patient-reported outcomes among patients who undergo surgical cervical sagittal realignment after kyphotic cervical spinal tuberculosis has been treated by débridement and reconstruction.

What Adverse Events and Injuries Are Cited in Anesthesia Malpractice Claims for Nonspine Orthopaedic Surgery?

Christopher D. Kent MD, Linda S. Stephens PhD, Karen L. Posner PhD, Karen B. Domino MD, MPH
2nd March 2017, Symposium: Learning From Large-Scale Orthopaedic Databases

Malpractice claims that arise during the perioperative care of patients receiving orthopaedic procedures will frequently involve both orthopaedic surgeons and anesthesiologists. The Anesthesia Closed Claims database contains anesthesia malpractice claim data that can be used to investigate patient safety events arising during the care of orthopaedic patients and can provide insight into the medicolegal liability shared by the two specialties.

Prediction of Polyethylene Wear Rates from Gait Biomechanics and Implant Positioning in Total Hip Replacement

Marzieh M. Ardestani PhD, Pedro P. Amenábar Edwards MD, Markus A. Wimmer PhD
2nd March 2017, Basic Research

Patient-specific gait and surgical variables are known to play an important role in wear of total hip replacements (THR). However a rigorous model, capable of predicting wear rate based on a comprehensive set of subject-specific gait and component-positioning variables, has to our knowledge, not been reported.

Increased Mortality After Prosthetic Joint Infection in Primary THA

Per Hviid Gundtoft MD, PhD, Alma Becic Pedersen MD, PhD, DMSc, Claus Varnum MD, PhD, Søren Overgaard MD, DMSc
24th February 2017, Clinical Research

Revision for prosthetic joint infection (PJI) has a major effect on patients’ health but it remains unclear if early PJI after primary THA is associated with a high mortality.