Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Online First™

Articles

Hyaluronic Acid-Based Hydrogel Coating Does Not Affect Bone Apposition at the Implant Surface in a Rabbit Model

W. Boot MSc, D. Gawlitta PhD, P. G. J. Nikkels MD, PhD, B. Pouran MSc, M. H. P. Rijen BSc, W. J. A. Dhert MD, PhD, H. Ch. Vogely MD, PhD
16th March 2017, Basic Research

Uncemented orthopaedic implants rely on the bone-implant interface to provide stability, therefore it is essential that a coating does not interfere with the bone-forming processes occurring at the implant interface. In addition, local application of high concentrations of antibiotics for prophylaxis or treatment of infection may be toxic for osteoblasts and could impair bone growth.

Have the Causes of Revision for Total and Unicompartmental Knee Arthroplasties Changed During the Past Two Decades?

Gro S. Dyrhovden MD, Stein Håkon L. Lygre PhD, Mona Badawy MD, PhD, Øystein Gøthesen MD, PhD, Ove Furnes MD, PhD
15th March 2017, Clinical Research

Revisions after knee arthroplasty are expected to increase, and the epidemiology of failure mechanisms is changing as new implants, technology, and surgical techniques evolve.

Sonication of Arthroplasty Implants Improves Accuracy of Periprosthetic Joint Infection Cultures

Adam C. Rothenberg MD, Alan E. Wilson BS, John P. Hayes, Michael J. O’Malley MD, Brian A. Klatt MD
13th March 2017, Symposium: 2016 Musculoskeletal Infection Society Proceedings

There is evidence that sonication of explanted prosthetic hip and knee arthroplasty components with culture of the sonication fluid may enhance diagnostic sensitivity. Previous studies on the use of implant sonicate cultures have evaluated diagnostic thresholds but did not elaborate on the clinical importance of positive implant sonicate cultures in the setting of presumed aseptic revisions and did not utilize consensus statements on periprosthetic joint infection (PJI) diagnosis when defining their gold standard for infection.

What Influence Does Progression of a Nonhealing Rotator Cuff Tear Have on Shoulder Pain and Function?

Yoon Sang Jeon MD, Rag Gyu Kim MD, Sang-Jin Shin MD
13th March 2017, Clinical Research

There have been numerous reports of clinical outcomes associated with tendon healing after repair that suggest a nonhealed tendon has a negative effect on postoperative clinical outcomes. However, to our knowledge, there has been no report on the relationship between tear size progression of nonhealed tendons and clinical outcomes.

What is the Ideal Route of Administration of Tranexamic Acid in TKA? A Randomized Controlled Trial

Sung Yup Lee MD, Suri Chong MD, Dhanasekaraprabu Balasubramanian MS (Orth), Young Gon Na MD, Tae Kyun Kim MD, PhD
10th March 2017, Clinical Research

TKA commonly involves substantial blood loss and tranexamic acid has been used to reduce blood loss after TKA. Numerous clinical trials have documented the efficacy and safety of intravenous (IV) or intraarticular (IA) use of tranexamic acid. Combined administration of tranexamic acid also has been suggested; however, there is no consensus regarding the ideal route of tranexamic acid administration.

Competency-based Medical Education—How Do We Get There?

Paul J. Dougherty MD, Pamela Andreatta PhD, EdD, MFA, CHSE
9th March 2017, CORR Curriculum — Orthopaedic Education