Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Online First™

Articles

Mondino de’ Liuzzi: The Restorer of Anatomy

Berardo Di Matteo MD, Vittorio Tarabella MA, Giuseppe Filardo MD, PhD, Massimiliano Mosca MD, Mirco Lo Presti MD, Anna Viganò MA, Patrizia Tomba MA, Maurilio Marcacci MD
4th January 2017, Art in Science

What Orthopaedic Operating Room Surfaces Are Contaminated With Bioburden? A Study Using the ATP Bioluminescence Assay

Raveesh Daniel Richard MD, Thomas R. Bowen MD
3rd January 2017, Symposium: 2016 Musculoskeletal Infection Society Proceedings

Contaminated operating room surfaces can increase the risk of orthopaedic infections, particularly after procedures in which hardware implantation and instrumentation are used. The question arises as to how surgeons can measure surface cleanliness to detect increased levels of bioburden. This study aims to highlight the utility of adenosine triphosphate (ATP) bioluminescence technology as a novel technique in detecting the degree of contamination within the sterile operating room environment.

Phosphatidylcholine Coatings Deliver Local Antimicrobials and Reduce Infection in a Murine Model: A Preliminary Study

Michael A. Harris BSBE, Karen E. Beenken PhD, Mark S. Smeltzer PhD, Warren O. Haggard PhD, J. Amber Jennings PhD
3rd January 2017, Symposium: 2016 Musculoskeletal Infection Society Proceedings

Phosphatidylcholine coatings have been shown to elute antibiotics for several days. A recently developed biofilm inhibitor, cis-2-decenoic acid (C2DA), has been shown to exhibit synergistic activity with several common antibiotics. This study aims to evaluate the effectiveness of C2DA and amikacin dual drug delivery from a phosphatidylcholine coating.

Racial Disparities in Above-knee Amputations After TKA: A National Database Study

Jaiben George MBBS, Suparna M. Navale MS, MPH, Nicholas K. Schiltz PhD, Miguel Siccha MD, Alison K. Klika MS, Carlos A. Higuera MD
19th December 2016, Symposium: 2016 Musculoskeletal Infection Society Proceedings

Above-knee amputation (AKA) is a rare but devastating complication of TKA. Although racial disparities have been previously reported in the utilization of TKA, it is unclear whether disparities exist in the rates of AKA after TKA.

False-positive Cultures After Native Knee Aspiration: True or False

Jason M. Jennings MD, DPT, Douglas A. Dennis MD, Raymond H. Kim MD, Todd M. Miner MD, Charlie C. Yang MD, David C. McNabb MD
9th December 2016, Symposium: 2016 Musculoskeletal Infection Society Proceedings

Synovial fluid aspiration is a routine practice used by most orthopaedic surgeons to aid in the diagnosis of joint infection. In patients for whom there is a low pretest probability of infection, a positive culture—particularly if it is a broth-only culture—may be considered a contaminant, especially if the bacterial species are skin pathogens. To our knowledge no study has evaluated the incidence of contamination of aspirations from the native knee.

Perioperative Risk Adjustment for Total Shoulder Arthroplasty: Are Simple Clinically Driven Models Sufficient?

David N. Bernstein MA, Aakash Keswani BA, David Ring MD, PhD
30th November 2016, Symposium: Learning From Large-Scale Orthopaedic Databases

There is growing interest in value-based health care in the United States. Statistical analysis of large databases can inform us of the factors associated with and the probability of adverse events and unplanned readmissions that diminish quality and add expense. For example, increased operating time and high blood urea nitrogen (BUN) are associated with adverse events, whereas patients on antihypertensive medications were more likely to have an unplanned readmission. Many surgeons rely on their knowledge and intuition when assessing the risk of a procedure. Comparing clinically driven with statistically derived risk models of total shoulder arthroplasty (TSA) offers insight into potential gaps between common practice and evidence-based medicine.

Results of Database Studies in Spine Surgery Can Be Influenced by Missing Data

Bryce A. Basques MD, Ryan P. McLynn BS, Michael P. Fice BS, Andre M. Samuel MD, Adam M. Lukasiewicz MD, MSc, Daniel D. Bohl MD, MPH, Junyoung Ahn MD, Kern Singh MD, Jonathan N. Grauer MD
28th November 2016, Symposium: Learning From Large-Scale Orthopaedic Databases

National databases are increasingly being used for research in spine surgery; however, one limitation of such databases that has received sparse mention is the frequency of missing data. Studies using these databases often do not emphasize the percentage of missing data for each variable used and do not specify how patients with missing data are incorporated into analyses. This study uses the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database to examine whether different treatments of missing data can influence the results of spine studies.

Anterolateral Ligament of the Knee Shows Variable Anatomy in Pediatric Specimens

Kevin G. Shea MD, Matthew D. Milewski MD, Peter C. Cannamela BS, Theodore J. Ganley MD, Peter D. Fabricant MD, Elizabeth B. Terhune BS, Alexandra C. Styhl BA, Allen F. Anderson MD, John D. Polousky MD
31st October 2016, Symposium: The 3rd Annual Meeting of Pediatric Research in Sports Medicine (PRISM)

Anterior cruciate ligament (ACL) reconstruction failure rates are highest in youth athletes. The role of the anterolateral ligament in rotational knee stability is of increasing interest, and several centers are exploring combined ACL and anterolateral ligament reconstruction for these young patients. Literature on the anterolateral ligament of the knee is sparse in regard to the pediatric population. A single study on specimens younger than age 5 years demonstrated the presence of the anterolateral ligament in only one of eight specimens; therefore, much about the prevalence and anatomy of the anterolateral ligament in pediatric specimens remains unknown.

Erratum to: Osteochondritis Dissecans Lesions in Family Members: Does a Positive Family History Impact Phenotypic Potency?

Alex L. Gornitzky MD, R. Justin Mistovich MD, Brittany Atuahene BA, Eileen P. Storey BA, Theodore J. Ganley MD
18th October 2016, Erratum