Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Online First™

Articles

What Orthopaedic Operating Room Surfaces Are Contaminated With Bioburden? A Study Using the ATP Bioluminescence Assay

Raveesh Daniel Richard MD, Thomas R. Bowen MD
3rd January 2017, Symposium: 2016 Musculoskeletal Infection Society Proceedings

Contaminated operating room surfaces can increase the risk of orthopaedic infections, particularly after procedures in which hardware implantation and instrumentation are used. The question arises as to how surgeons can measure surface cleanliness to detect increased levels of bioburden. This study aims to highlight the utility of adenosine triphosphate (ATP) bioluminescence technology as a novel technique in detecting the degree of contamination within the sterile operating room environment.

What is the Accuracy of Nuclear Imaging in the Assessment of Periprosthetic Knee Infection? A Meta-analysis

Steven J. Verberne MD, Remko J. A. Sonnega MD, Olivier P. P. Temmerman MD, PhD, Pieter G. Raijmakers MD, PhD
3rd January 2017, Meta-analysis

In the assessment of possible periprosthetic knee infection, various imaging modalities are used without consensus regarding the most accurate technique.

Preventing Fusion Mass Shift Avoids Postoperative Distal Curve Adding-on in Adolescent Idiopathic Scoliosis

Hideki Shigematsu MD, PhD, Jason Pui Yin Cheung MBBS (HK), MMedSc, FRCS (Edin), FHKCOS, FHKAM (Orth), Mauro Bruzzone MD, Hiroaki Matsumori MD PhD, Kin-Cheung Mak MBBS, FRCSEd, FHKCOS, FHKAM (Orth), Dino Samartzis DSc, Keith Dip Kei Luk MCh (Orth), FRCSE, FRCSG, FRACS, FHKAM (Orth)
3rd January 2017, Clinical Research

Surgery for adolescent idiopathic scoliosis (AIS) is only complete after achieving fusion to maintain the correction obtained intraoperatively. The instrumented or fused segments can be referred to as the “fusion mass”. In patients with AIS, the ideal fusion mass strategy has been established based on fulcrum-bending radiographs for main thoracic curves. Ideally, the fusion mass should achieve parallel endplates of the upper and lower instrumented vertebra and correct any “shift” for truncal balance. Distal adding-on is an important element to consider in AIS surgery. This phenomenon represents a progressive increase in the number of vertebrae included distally in the primary curvature and it should be avoided as it is associated with unsatisfactory cosmesis and an increased risk of revision surgery. However, it remains unknown whether any fusion mass shift, or shift in the fusion mass or instrumented segments, affects global spinal balance and distal adding-on after curve correction surgery in patients with AIS.

Phosphatidylcholine Coatings Deliver Local Antimicrobials and Reduce Infection in a Murine Model: A Preliminary Study

Michael A. Harris BSBE, Karen E. Beenken PhD, Mark S. Smeltzer PhD, Warren O. Haggard PhD, J. Amber Jennings PhD
3rd January 2017, Symposium: 2016 Musculoskeletal Infection Society Proceedings

Phosphatidylcholine coatings have been shown to elute antibiotics for several days. A recently developed biofilm inhibitor, cis-2-decenoic acid (C2DA), has been shown to exhibit synergistic activity with several common antibiotics. This study aims to evaluate the effectiveness of C2DA and amikacin dual drug delivery from a phosphatidylcholine coating.

Is There Benefit to Free Over Pedicled Vascularized Grafts in Augmenting Tibial Intercalary Allograft Constructs?

Marco Manfrini MD, Srimanth Bindiganavile MD, Ferhat Say MD, Marco Colangeli MD, Laura Campanacci MD, Massimiliano Depaolis MD, Massimo Ceruso MD, Davide Donati MD
19th December 2016, Clinical Research

Intercalary reconstruction of tibial sarcomas with vascularized fibula autografts and massive bone allografts is reliable with predictable long-term results. However, inadequate data exist comparing free and pedicled vascularized fibula autografts in combination with a massive bone allograft in patients undergoing intercalary tibia reconstructions.

Racial Disparities in Above-knee Amputations After TKA: A National Database Study

Jaiben George MBBS, Suparna M. Navale MS, MPH, Nicholas K. Schiltz PhD, Miguel Siccha MD, Alison K. Klika MS, Carlos A. Higuera MD
19th December 2016, Symposium: 2016 Musculoskeletal Infection Society Proceedings

Above-knee amputation (AKA) is a rare but devastating complication of TKA. Although racial disparities have been previously reported in the utilization of TKA, it is unclear whether disparities exist in the rates of AKA after TKA.

False-positive Cultures After Native Knee Aspiration: True or False

Jason M. Jennings MD, DPT, Douglas A. Dennis MD, Raymond H. Kim MD, Todd M. Miner MD, Charlie C. Yang MD, David C. McNabb MD
9th December 2016, Symposium: 2016 Musculoskeletal Infection Society Proceedings

Synovial fluid aspiration is a routine practice used by most orthopaedic surgeons to aid in the diagnosis of joint infection. In patients for whom there is a low pretest probability of infection, a positive culture—particularly if it is a broth-only culture—may be considered a contaminant, especially if the bacterial species are skin pathogens. To our knowledge no study has evaluated the incidence of contamination of aspirations from the native knee.