27th April 2017, Basic Research
Proliferative therapy, or prolotherapy, is a controversial treatment method for many connective tissue injuries and disorders. It involves the injection of a proliferant, or irritant solution, into the site of injury, which causes small-scale cell death. This therapeutic trauma is theorized to initiate the body’s wound-healing cascade, perhaps leading to tissue repair. The immediate effects of many of these proliferants are poorly characterized, as are the cellular responses to them; here, we sought to evaluate the immediate effects of two common proliferants (dextrose and P2G, a combination of phenol, glucose, and glycerin) on the cellular response of human tenocytes, and begin to explicate the mechanisms with which each proliferant functions.
Variations in Knee Kinematics After ACL Injury and After Reconstruction Are Correlated With Bone Shape Differences
27th April 2017, Symposium: Improving Care for Patients With ACL Injuries: A Team Approach
The factors that contribute to the abnormal knee kinematics after anterior cruciate ligament (ACL) injury and ACL reconstruction remain unclear. Bone shape has been implicated in the development of hip and knee osteoarthritis, although there is little knowledge about the effects of bone shape on knee kinematics after ACL injury and after ACL reconstruction.
25th April 2017, Symposium: 2016 Musculoskeletal Infection Society Proceedings
Cochrane in CORR
24th April 2017, Cochrane in CORR